Effect of rhodiola on serum troponin 1, cardiac integral backscatter and left ventricle ejective fraction of patients who received epirubicin-contained chemotherapy / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
;
(12): 1250-1252, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-327460
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the myocardial protective effect of Rhodiola on patients who received epidoxorubicin (EPI) treatment.</p><p><b>METHODS</b>Forty-two patients with myocardial damage who received 3 courses of EPI-contained chemotherapy were randomly and equally assigned to two groups, the Rhodiola treated group and the control group. After 1-month treatment, the changes in serum troponin I (cTnI) level, cardiac integral backscatter (IBS), and left ventricle ejective fraction (LVEF) in patients were observed and compared between groups.</p><p><b>RESULTS</b>Levels of cTnI in the treated group and control group were (0.54 +/- 0.05) mg/L and (0.98 +/- 0.03) mg/L respectively, IBS were 55.23 +/- 5.72 scores and 61.23 +/- 5.96 scores, and LVEF (%) were 68 +/- 3 and 57 +/- 2 respectively, all showed significant differences between groups (P<0.05).</p><p><b>CONCLUSION</b>Rhodiola can improve cardiac function, and suppress the increase of serum cTnI level and IBS in patients who received EPI treatment.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Postoperative Period
/
Stomach Neoplasms
/
Stroke Volume
/
General Surgery
/
Blood
/
Breast Neoplasms
/
Drugs, Chinese Herbal
/
Epirubicin
/
Antineoplastic Combined Chemotherapy Protocols
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Integrated Traditional and Western Medicine
Year:
2010
Type:
Article
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