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Difference of dilation resistance to coronary stenting between fibrous plaques and lipid-rich plaques / 中华医学杂志(英文版)
Chinese Medical Journal ; (24): 4149-4153, 2013.
Article in English | WPRIM | ID: wpr-327616
ABSTRACT
<p><b>BACKGROUND</b>Dilation resistance to stenting in non-calcified coronary plaques was compared in patients with percutaneous coronary intervention (PCI) in order to confirm the clinical usefulness of multislice computed tomography in examining coronary plaque type and to provide information pertaining to the effects of plaque type on dilatation resistance.</p><p><b>METHODS</b>A retrospective analysis of 64-slice computed tomography coronary imaging data collected in the month prior to coronary stenting in 93 patients (65 male and 28 female, mean age of (57.22±7.22) years) was conducted. Non-calcified coronary plaques were divided into lipid-rich (lipid content >25% of plaque volume) and fibrous plaques according to the Hammer-Hansen S

method:

where lipids, fiber, and intraluminal components were indicated by contrast using Hu values of -100-49, 50-129, and >130, respectively. Clinical features, pre-dilatation balloon specifications and filling pressure, and stent size and release pressure were compared.</p><p><b>RESULTS</b>High-sensitivity C-reactive protein levels were higher in the lipid-rich plaque group. In patients with typical symptoms, unstable angina was more commonly observed in the lipid-rich plaque group. No significant differences in low density lipoprotein, pre-dilatation balloon specifications, pre-dilatation pressure, or stent specifications were observed. Stent release pressure in the lipid-rich plaque group ((1130.16±202.04) kPa), was significantly lower than that observed in the fibrous plaque group ((1240.61±193.29) kPa, P = 0.009).</p><p><b>CONCLUSION</b>Softer, lipid-rich plaques exhibit lower dilation resistance during stenting in PCI patients.</p>
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Pathology / Physiology / General Surgery / Coronary Artery Disease / C-Reactive Protein / Retrospective Studies / Coronary Angiography / Plaque, Atherosclerotic / Multidetector Computed Tomography / Percutaneous Coronary Intervention Type of study: Observational study Limits: Female / Humans / Male Language: English Journal: Chinese Medical Journal Year: 2013 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pathology / Physiology / General Surgery / Coronary Artery Disease / C-Reactive Protein / Retrospective Studies / Coronary Angiography / Plaque, Atherosclerotic / Multidetector Computed Tomography / Percutaneous Coronary Intervention Type of study: Observational study Limits: Female / Humans / Male Language: English Journal: Chinese Medical Journal Year: 2013 Type: Article