Study on extracting process of ethanol extract with hypouricemic effect from rhizoma alismatis / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 1809-1811, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-328028
ABSTRACT
<p><b>OBJECTIVE</b>To optimize the extracting process of ethanol extract with hypouricemic effect from Rhizoma Alismatis.</p><p><b>METHOD</b>Orthogonal design was utilized to optimize the preparing conditions including the concentration of ethanol, amount of ethanol, extraction times and extraction duration per time while alisol B 23-acetate was selected as the evaluation index. Both the alisol B 23-acetate and the serum uric acid levels were measured by HPLC.</p><p><b>RESULT</b>The ethanol extract had hypouricemic action. Only extraction times had significant effect on the content of alisol B 23-acetate in ethanol extract.</p><p><b>CONCLUSION</b>The optimal extraction process is to extract two times using sevenfold 70% ethanol and 1 h per time.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Uric Acid
/
Blood
/
Plant Extracts
/
Chemistry
/
Uricosuric Agents
/
Rhizome
/
Alismataceae
/
Hyperuricemia
/
Disease Models, Animal
/
Ethanol
Limits:
Animals
/
Humans
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2010
Type:
Article
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