In vitro senstivity of sporothrix schenckii against antifungal agents / 대한피부과학회지
Korean Journal of Dermatology
;
: 884-889, 1993.
Article
in Korean
| WPRIM
| ID: wpr-32811
ABSTRACT
BACKGROUND:
Despite concern about treatment of sporotrichosis, little is known about the sensitivity of S. schenckii against antifungal agents.OBJECTIVE:
The purpose of the study was to investigate minimal irihibitory concentration(MIC) of antifungal agents against S.chenckii.METHOD:
The tested strains were seven in number. The tested antifngal agents were ketoconazole, itraconazole, amphotericin B, and potassium iodide. A various concentration of drugs were mixed into fluid media containing 50% ethanol, dimethyl sulfoxide, and distilled water. The inoculum consisted of 3mm block containing hyphae and spores.RESULTS:
MIC ranges of ket.oconazole, itraconazole, amphotericin B, and potassium iodide were 0.39- 25pg/ml, 0.78-25pg/ml, 0.78-25pg/ml, and 75-550pg/ml, respectively.CONCLUSION:
We find that ketoconazole is the most active drug against S. schenckii.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Potassium Iodide
/
Spores
/
Sporotrichosis
/
Sporothrix
/
Water
/
Amphotericin B
/
Dimethyl Sulfoxide
/
Itraconazole
/
Hyphae
/
Ethanol
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
1993
Type:
Article
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