Impact of fenestration on early outcome in patients undergoing modified Fontan operation / 中华心血管病杂志

ABSTRACT

<p><b>OBJECTIVE</b>To compare the impact of fenestration on early outcome in patients undergoing modified Fontan operation.</p><p><b>METHODS</b>Data from 90 consecutive patients underwent modified Fontan operation from November 2008 to June 2013 were retrospectively analyzed. Patients were divided into fenestrated group (49 patients) and non-fenestrated group (41 patients) and early outcome post operation was compared between the two groups.</p><p><b>RESULTS</b>Anatomy, age, gender, body weight and disease classifications were similar between the two groups (all P > 0.05). Postoperative central venous pressure was (11.4 ± 4.1) mmHg (1 mmHg = 0.133 kPa) in fenestrated group and (12.1 ± 3.8) mmHg in non-fenestrated group (P = 0.894). The duration of chest tube drainage was (11.1 ± 9.2) day in fenestrated group and (15.0 ± 10.7) day in non-fenestrated group (P = 0.160). Volume of pleural drainage was 772.0 (411.5-1 971.5) ml in fenestrated group and 1 259.0 (571.0-2 647.5) ml in non-fenestrated group (P = 0.214). Duration of ICU stay was 24.0 (18.0-40.0) day in fenestrated group and 24.0 (19.0-36.0) day in non-fenestrated group (P = 0.751). The time of respirator use was 9.0 (6.0-15.0) hours in fenestrated group and 8.0 (6.0-16.0) hours in non-fenestrated group (P = 0.951). Duration of hospital stay was significantly longer in fenestrated group than in non-fenestrated group ((32.7 ± 23.0) day vs. (27.8 ± 12.6) day, P = 0.025). One patient (2.0%) died of low cardiac output syndrome in fenestrated group and 1 patient (2.4%) experienced hydropericardium in non-fenestrated group. The incidence rate of complications (P = 0.898) and mortality (P = 1.000) were similar between the two groups.</p><p><b>CONCLUSION</b>Early outcome is similar for patients undergoing the modified Fontan operation with or without fenestration.</p>