High performance liquid chromatography characteristic spectrum of artificial musk / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 587-590, 2014.
Article
in English
| WPRIM
| ID: wpr-329780
ABSTRACT
<p><b>OBJECTIVE</b>To determine the high performance liquid chromatography(HPLC)characteristic spectrum of artificial musk.</p><p><b>METHODS</b>HPLC was performed on a HiQ Sil C18 analytical column(4.6 mm×250 mm)with the mobile phase of methanol/water(9010 v/v);the detection wavelength was 254 nm and the column temperature was maintained at 25 ℃. The similarities among 10 batches of artificial musk samples were anlysised in accordance with the System for Evaluating the Similarities among the Chromatographic Fingerprints of Traditional Chinese Drugs,which is recommended by Chinese Pharmacopoeia Commission.</p><p><b>RESULT</b>The similarities among these 10 batches of artificial musk ranged between 0.999 and 1.000.</p><p><b>CONCLUSION</b>HPLC is a convenient,accurate and reliable technique for establishing the specific spectum of artificial musk and therefore can be used for the quality control of this product.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Quality Control
/
Drugs, Chinese Herbal
/
Fatty Acids, Monounsaturated
/
Chemistry
/
Chromatography, High Pressure Liquid
/
Medicine, Chinese Traditional
Type of study:
Diagnostic study
Language:
English
Journal:
Acta Academiae Medicinae Sinicae
Year:
2014
Type:
Article
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