Effects of dipeptidyl peptidase-4 on the hematopoiesis and transplantation / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 538-541, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-329789
ABSTRACT
Dipeptidyl peptidase-4 (DPP-4) is a protease that cleaves the peptides with alanine, praline, or other selective amino acids at the N-terminal penultimate position. The substrates of DPP-4 include many chemokines, colony-stimulating factors, and interleukins. Recent research has shown that DPP-4 can affect the hematopoietic stem and progenitor cells and transplantation by truncating the granulocyte colony stimulating factor. However, its regulatory effect on DPP-4 and most peptides truncation are still unknown. This review summarizes the recent advances in the DPP-4 research.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Hematopoietic Stem Cell Transplantation
/
Dipeptidyl Peptidase 4
/
Hematopoiesis
Limits:
Humans
Language:
Chinese
Journal:
Acta Academiae Medicinae Sinicae
Year:
2014
Type:
Article
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