Endoscopic Ultrasound-Guided Fine Needle Aspiration Cytology Diagnosis of Solid Pseudopapillary Neoplasm: Three Case Reports with Review of Literature
Korean Journal of Pathology
;
: 399-406, 2012.
Article
in English
| WPRIM
| ID: wpr-32980
ABSTRACT
Solid pseudopapillary neoplasm of the pancreas (SPN) is relatively rare and it occurs almost exclusively in women. We recently experienced three cases of SPN diagnosed by endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA). These three cases were two male and one female patient whose age was 29, 37, and 44 years old. Radiological diagnosis was pancreatic endocrine tumor (PEN) showing solid with a heterogenous echogenicity. EUS-FNA cytology specimens consisted of single cells and aggregates of uniform cells, forming microadenoid structures, branching, papillary clusters with delicate fibrovascular cores. In conclusion, a single diagnosis of SPN based on clinical and radiological findings would be risky because there is a possibility of it being misdiagnosed as PEN or other malignancies. An EUS-FNA is therefore essential for establishing the diagnosis. In addition, the pathologists should recognize the characteristic cytologic findings with immunoprofiles of SPN to prevent misdiagnosis of SPN.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pancreas
/
Biopsy, Fine-Needle
/
Diagnostic Errors
/
Endoscopic Ultrasound-Guided Fine Needle Aspiration
Type of study:
Controlled clinical trial
/
Diagnostic study
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Korean Journal of Pathology
Year:
2012
Type:
Article
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