Comparison of 3D pseudo-continuous arterial spin labeling and positron emission tomography-computed tomography in the brain disorders / 中国医学科学院学报

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the diagnostic agreement of 3D pseudo-continuous arterial spin labeling (3D-pCASL) and ¹⁸F-fluorodeoxyglucose and ¹¹C-Methionine positron emission tomography-computed tomography(PET/CT) for brain disorders.</p><p><b>METHOD</b>3D-pCASL and PET/CT were performed on 7 patients with different brain disorders, and the diagnostic agreement was assessed by visual observation.</p><p><b>RESULTS</b>Four tumor lesions presented hyperperfusion on 3D-pCASL, and hypermetabolism on PET/CT. One demyelinated lesion and one metabolic lesion showed hyperperfusion on 3D-pCASL, and one infected lesion showed hypoperfusion on 3D-pCASL ;all these three lesions showed hypermetabolism on PET/CT.</p><p><b>CONCLUSION</b>3D-pCASL can non-invasively evaluate the perfusion state of the brain disorder in vivo and have a good dignostic consistency with PET/CT.</p>