Ultrasonographic features of thyroid nodules accompanied by Hashimoto thyroiditis / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 261-266, 2014.
Article
in English
| WPRIM
| ID: wpr-329837
ABSTRACT
<p><b>OBJECTIVE</b>To compare the ultrasound imaging characteristics of benign and malignant thyroid nodules on the background of Hashimoto's thyroiditis (HT).</p><p><b>METHODS</b>Totally 120 consecutive patients with pathologically confirmed benign (n=60) or malignant (n=60) thyroid nodules in Peking Union Medical College Hospital since January 2013 were retrospectively analyzed, and their preoperative ultrasound images were reviewed.</p><p><b>RESULTS</b>Sixty cases (100%) of the malignant nodules were papillary thyroid cancers. In the benign group, 33 cases (55.0%) had nodular changes of HT, 26 (43.3%) had nodular goiter, and one (16.7%) had adenoma. Compared with the benign ones,the malignant nodules were more likely to be solid (91.7% vs. 68.3%, P=0.001), hypoechoic (96.7% vs. 48.3%, P=0.000), ill defined (95.0% vs. 41.7%, P=0.000), irregular (96.7% vs. 43.4%, P=0.000), and more easily to have such characteristics as micro-calcification (71.7% vs. 30.0%, P=0.000), absence of regular halo (96.7% vs. 65.0%, P=0.000), taller-than-wide sign (46.7% vs. 13.3%, P=0.000), and locally increased or irregular blood flow (61.7% vs. 26.7%, P=0.000).</p><p><b>CONCLUSIONS</b>Ultrasound has an ideal overall sensitivity in differentiating nodules on the background of HT. Solid structure, hypo-echogenicity, ill-defined margin, irregular shape, and absence of regular halo are good screening ultrasound markers. Except for the A/T≥1, the other variables have less satisfactory diagnostic specificity.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Thyroid Neoplasms
/
Diagnostic Imaging
/
Retrospective Studies
/
Ultrasonography
/
Sensitivity and Specificity
/
Thyroid Nodule
/
Hashimoto Disease
Type of study:
Diagnostic study
/
Observational study
Limits:
Adult
/
Humans
Language:
English
Journal:
Acta Academiae Medicinae Sinicae
Year:
2014
Type:
Article
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