Research advances in epithelial-mesenchymal transition in thyroid carcinoma / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 218-222, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-329844
ABSTRACT
Increasing evidences have demonstrated the roles of epithelial-mesenchymal transition in tumor invasion and metastasis. In the invasive front of papillary thyroid carcinoma, the expressions of adhesion molecules are often lost. In anaplastic thyroid carcinoma, tumor cells showing cancer stem cell characteristics have been identified. Epithelial-mesenchymal transition may thus play a key role in the progression of thyroid cancer. Therefore, it provide new insight for the development of targeted drugs for anaplastic thyroid carcinoma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Transcription Factors
/
Thyroid Neoplasms
/
Cadherins
/
Epithelial-Mesenchymal Transition
/
Metabolism
Type of study:
Prognostic study
Limits:
Humans
Language:
Chinese
Journal:
Acta Academiae Medicinae Sinicae
Year:
2014
Type:
Article
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