Effect of overload environment on IGF-1 expression of osteoblasts

Juanfang SHANG; Liling TANG; Xufeng NIU; Yuanliang WANG

Effect of overload environment on IGF-1 expression of osteoblasts / 生物医学工程学杂志

Juanfang SHANG; Liling TANG; Xufeng NIU; Yuanliang WANG.

Journal of Biomedical Engineering ; (6): 1363-1366, 2006.

Article in Chinese | WPRIM | ID: wpr-331411

ABSTRACT

ABSTRACT

In the study of the relationship between cells overloading and the formation, regeneration and growth of bone, the text discussed osteoblasts express IGF-1 variation under overloading environment. The research of overloading on cellular level may elucidate the mechanical effect on the formation, regeneration and growth of bone and the mechanism of cell response in bone.

Subject(s)

Animals; Humans; Insulin-Like Growth Factor I; Genetics; Osteoblasts; Cell Biology; Metabolism; Osteogenesis; RNA, Messenger; Genetics; Stress, Mechanical; Weight-Bearing; Physiology

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Osteoblasts / Osteogenesis / Physiology / Stress, Mechanical / RNA, Messenger / Insulin-Like Growth Factor I / Weight-Bearing / Cell Biology / Genetics / Metabolism Limits: Animals / Humans Language: Chinese Journal: Journal of Biomedical Engineering Year: 2006 Type: Article

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