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Construction recombinant adenovirus vector expressing murine endostatin and inhibition of blood endothelial cells growth / 生物医学工程学杂志
Journal of Biomedical Engineering ; (6): 1294-1297, 2006.
Article in Chinese | WPRIM | ID: wpr-331427
ABSTRACT
We constructed recombinant adenovirus vector expressing murine endostatin and evaluated the Inhibition of human umbilical vein endothelial cells (HUVEC). We proved that endostatin significantly suppressed the S phase fraction, inhibited proliferation and increased the apoptotic index of HUVEC.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pharmacology / Umbilical Veins / Recombinant Proteins / Cells, Cultured / Adenoviridae / Apoptosis / Cell Biology / Endothelial Cells / Endostatins / Cell Proliferation Limits: Animals / Humans Language: Chinese Journal: Journal of Biomedical Engineering Year: 2006 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pharmacology / Umbilical Veins / Recombinant Proteins / Cells, Cultured / Adenoviridae / Apoptosis / Cell Biology / Endothelial Cells / Endostatins / Cell Proliferation Limits: Animals / Humans Language: Chinese Journal: Journal of Biomedical Engineering Year: 2006 Type: Article