Clinical research on effects of yunpi zhixie granule in children with diarrhea / 中国中西医结合杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the clinical effect of Yunpi Zhixie Granule (YZG) on children's diarrhea.</p><p><b>METHODS</b>Three hundred diarrhea cases were randomly divided into two groups equally, the treated group treated by YZG orally and the control group by smacta, both for 7 days. The clinical efficacy was observed, routine scatologic analysis, scatologic cultivation, rotavirus antigen and urinary D-xylose content were detected.</p><p><b>RESULTS</b>Clinical results showed the effective rate in treating the chronic or Pi-deficiency diarrhea as well as the negative conversion rate and improvement rate of routine scatologic analysis were all higher in the treated group than those in the control group (P < 0.05); while no significant difference was found in negative conversion rate of scatologic cultivation and rotavirus antigen and urinary D-xylose content after treatment, compared with those before treatment (P > 0.05).</p><p><b>CONCLUSION</b>YZG was effective in treating children' s diarrhea, especially on chronic diarrhea and diarrhea of Pi-deficiency type.</p>