Effects of modified longdan xiegan decoction on hyperandrogenism in patients with polycystic ovary syndrome of stagnant fire in Gan channel type / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
;
(12): 838-841, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-331969
ABSTRACT
<p><b>OBJECTIVE</b>To observe the therapeutic effect of modified Longdan Xiegan Decoction (LXD) on hyperandrogenism in patients with polycystic ovary syndrome (POS) of stagnant fire in Gan channel type.</p><p><b>METHODS</b>Forty-eight patients were divided into two groups the LXD group (25 cases) treated with LXI) for 3 months, and the Diane-35 group (23 cases) with Diane-35. Condition of menstruation, acne, hairiness were observed, basal body temperature (BBT) was measured, and the serum levels of luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (PRL), free testosterone (FT), and androstenedione (A) were detected before and after 3 months' treatment. Meanwhile, adverse reaction was observed.</p><p><b>RESULTS</b>After treatment, the condition of menstrual disorder, acne and single-phase BBT were improved significantly, and serum levels of LH, LH/FSH, FT and A decreased in both groups (P < 0.05), showed insignificant difference between them (P > 0.05). The PRL level dropped in the LXD group (P < 0.05), which significantly lower than that in the Diane-35 group (P < 0.05). There were 3 cases with adverse reaction of irregular colporrhagia and 5 cases with nausea and vomiting in the Diane-35 group, while no adverse reaction in the LXD group occurred.</p><p><b>CONCLUSION</b>Modified LXD could significantly improve the condition in hyperandrogenism patients with POS of stagnant fire in Gan channel type.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Polycystic Ovary Syndrome
/
Drugs, Chinese Herbal
/
Hyperandrogenism
/
Therapeutic Uses
/
Drug Therapy
/
Medicine, Chinese Traditional
/
Phytotherapy
Type of study:
Diagnostic study
Limits:
Adolescent
/
Adult
/
Female
/
Humans
Language:
Chinese
Journal:
Chinese Journal of Integrated Traditional and Western Medicine
Year:
2006
Type:
Article
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