The level of TNF-alpha secretion of PBMC in patients with chronic hepatitis C and nonalcoholic fatty liver / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 109-111, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-332413
ABSTRACT
<p><b>OBJECTIVE</b>To study the roles of TNF-alpha secretion of PBMC in patients with chronic hepatitis C and Nonalcoholic fatty liver.</p><p><b>METHODS</b>The level of TNF-alpha secretion of PBMC in patients with chronic hepatitis C and Nonalcoholic fatty liver was detected by ELISA after culturing for 72 hours in vitro, as well as patients with chronic hepatitis C and the normal control.</p><p><b>RESULTS</b>(1) Compared with the normal control, the level of TNF-alpha in group with chronic hepatitis C and in group with chronic hepatitis C and Nonalcoholic fatty liver notably increased. (2) Compared with the group with chronic hepatitis C, the level of TNF-alpha in group with chronic hepatitis C and Nonalcoholic fatty liver also notably increased.</p><p><b>CONCLUSION</b>It suggested TNF-alpha takes important roles in the infection course of chronic hepatitis C with Nonalcoholic fatty liver.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Leukocytes, Mononuclear
/
Cells, Cultured
/
Tumor Necrosis Factor-alpha
/
Hepatitis C, Chronic
/
Fatty Liver
/
Metabolism
Limits:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Experimental and Clinical Virology
Year:
2009
Type:
Article
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