Research progress of N-Myc roles in hematopoiesis and hematologic malignancies / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 503-507, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-332748
ABSTRACT
N-Myc oncogene plays an important role in the process of hematopoietic cell proliferation and differentiation in embryos. Once the body suffers from hematologic malignancies, the expression of N-Myc would increase and significantly associate with disease progression. In this article the structure of N-Myc, the regulatory mechanism in the different hematopoietic lineages, the interaction in each signal pathways, the transgenic animal model of overexpression, and intervention by drugs are reviewed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Proto-Oncogene Proteins c-myc
/
Hematologic Neoplasms
/
Hematopoiesis
/
Metabolism
Limits:
Humans
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2013
Type:
Article
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