Study on treatment effectiveness and safety in children with chronic hepatitis B or C using bicyclo tablets / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 380-382, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-333001
ABSTRACT
<p><b>BACKGROUND</b>To evaluate treatment effectiveness and safety of bicyclo tablets in children with chronic hepatitis B or C.</p><p><b>METHODS</b>A randomized controlled trial was conducted in 148 children with chronic hepatitis B or C for evaluating safety, tolerability, and efficacy of treatment with bicyclo tablets or Hugan tablets. Children in therapy group were treated with bicyclo tablets and control group treated with Hugan tablets.</p><p><b>RESULTS</b>(1) ALT and AST level decreased more prominently in therapy group than in control group (P<0.01). (2) Bicyclo was more effective than Hugan tablets (P<0.01). (3) Symptoms were ameliorated more prominently in bicyclo group than in control group (P<0.01). (4) Both groups had no significant adverse events.</p><p><b>CONCLUSION</b>Satisfactory therapeutic effect and safety were obtained with bicyclo tablets in children with chronic hepatitis B or C.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Tablets
/
Biphenyl Compounds
/
Treatment Outcome
/
Hepatitis B, Chronic
/
Hepatitis C, Chronic
/
Therapeutic Uses
/
Drug Therapy
Type of study:
Controlled clinical trial
Limits:
Adolescent
/
Child
/
Child, preschool
/
Humans
Language:
Chinese
Journal:
Chinese Journal of Experimental and Clinical Virology
Year:
2005
Type:
Article
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