Screening for new binding proteins which interact with BM2 of influenza B virus with yeast two-hybrid system / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 182-184, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-333067
ABSTRACT
<p><b>OBJECTIVE</b>To explore the role of BM2 protein in the life cycle of influenza B virus.</p><p><b>METHODS</b>The authors screened human kidney MATCHMAKER cDNA library for new binding partners of BM2 of influenza B virus by using the yeast two hybrid system with truncated BM2 (26-109 aa) as the bait.</p><p><b>RESULTS</b>Six positive plasmids encoding N-acetylneuraminate pyruvate lyase, angiopoietin 3, zinc finger protein 251, ribosomal protein S20, protein arginine N-methyltransferase 1 variant 1 (PRMT) and transcription factor-like 1 (TCFL1) were obtained.</p><p><b>CONCLUSION</b>The results suggest that BM2 may play an important role in the life cycle of influenza B virus.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Influenza B virus
/
Plasmids
/
Protein-Arginine N-Methyltransferases
/
Protein Binding
/
Repressor Proteins
/
Ribosomal Proteins
/
Transcription Factors
/
Viral Proteins
/
Gene Library
/
Zinc Fingers
Type of study:
Diagnostic study
/
Screening study
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Experimental and Clinical Virology
Year:
2005
Type:
Article
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