Mitochondria couple cellular Ca(2+) signal transduction / 生理学报
Acta Physiologica Sinica
;
(6): 333-340, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-333193
ABSTRACT
It has been shown that mitochondria not only control their own Ca(2+) concentration ([Ca(2+)]), but also exert an influence over Ca(2+) signaling of the entire cell, including the endoplasmic reticulum or the sarcoplasmic reticulum, the plasma membrane, and the nucleus. That is to say, mitochondria couple cellular metabolic state with Ca(2+) transport processes. This review focuses on the ways in which the mitochondrial Ca(2+) handling system provides integrity and modulation for the cell to cope with the complex actions throughout its life cycle, enumerates some indeterminate aspects about it, and finally, prospects directions of future research.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Sarcoplasmic Reticulum
/
Biological Transport
/
Cell Membrane
/
Calcium Signaling
/
Endoplasmic Reticulum
/
Mitochondria
Language:
Chinese
Journal:
Acta Physiologica Sinica
Year:
2012
Type:
Article
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