Epidemiological survey of high-risk human papillomavirus among 2501 woman / 南方医科大学学报
Journal of Southern Medical University
;
(12): 1487-1491, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-333599
ABSTRACT
<p><b>OBJECTIVE</b>To survey the prevalence of high-risk human papillomavirus (HPV) in woman in Guangzhou during the period from 2013 to 2014.</p><p><b>METHODS</b>A total of 2501 women in Guangzhou seeking medical attention in our hospital underwent high-risk HPV genotype screening of cervical specimens using real-time PCR.</p><p><b>RESULTS</b>The prevalence of high-risk HPV infection among the women was 14.85% (146/983) in the year 2013, similar to the rate of 14.56% (221/1518) in 2014 (Χ(2)=0.041, P=0.839); no significant differences were found in the high-risk HPV infection rates between different age groups in either 2013 (Χ(2)=2.916, P=0.572) or 2014 (Χ(2)=6.494, P=0.165). The constituent ratio of the 13 types of high-risk HPV showed no significant difference between 2013 and 2014 (Χ(2)=11.872, P=0.452). The 13 HPV genotypes detected, listed in a descending order of the constituent ratios, included HPV-52, -16, -58, -56, -39, -51, -68, -59, -31, -35, -18, -33 and -45 in 2013, and were HPV-52, -16, -58, -68, -18, -51, -56, -39, -31, -33, -59, -35 and-45 in 2014.</p><p><b>CONCLUSION</b>We report a high prevalence of high-risk HPV among women in Guangzhou, which suggests the necessity of screening for high-risk HPV-DNA among women at all ages for prevention and early detection of cervical cancer.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Papillomaviridae
/
Virology
/
Uterine Cervical Neoplasms
/
China
/
Epidemiology
/
Prevalence
/
Risk Factors
/
Classification
/
Papillomavirus Infections
/
Real-Time Polymerase Chain Reaction
Type of study:
Etiology study
/
Prevalence study
/
Risk factors
/
Screening study
Limits:
Female
/
Humans
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2015
Type:
Article
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