Application df/dt(max) index for determinations of skeletal contractility / 中国应用生理学杂志

ABSTRACT

<p><b>AIM</b>To analyze the most force rising ratio (+ dF/dt(max)) and the most force descending ratio (- dF/dt(max)) for more sensitive index of skeletal contractility.</p><p><b>METHODS</b>Mouse model of swimming training was used, most force (f(max)), + dF/dt(max) and - dF/ dt(max) of gastrocnemius contracting were measured and changes of gastrocnemius supermicro-structure was observed.</p><p><b>RESULTS</b>Mitochondria increased and myoneme was regular in general training load, gastrocnemius F(max) - dF/dt(max) significantly increased than in control (P < 0.05), + dF/dt(max) increased more significantly (P < 0.01). Mitochondria was rare and myoneme was unusual in overtraining load, gastrocnemius F(max), - dF/dt(max) reduced significantly than in control (P < 0.05), + dF/dt(max) reduced more significantly (P < 0.01).</p><p><b>CONCLUSION</b>+ dF/dt(max) is better index than F(max) in judging skeletal contractility.</p>