Habenula participates the vasopressor response by stimulation of the insular cortex, central-, lateral amygdaloid nucleus respectively / 中国应用生理学杂志

ABSTRACT

<p><b>AIM</b>To investigate whether if the Habenula is the main relay involved in the vasopressor effect induced by the stimulus of insular cortex, central-, lateral amygdaloid nucleus respectively.</p><p><b>METHODS</b>Electrostimulation of the nuclei mention above respectively, and microinjection of lidocaine into Habenula unilaterally and bilaterally.</p><p><b>RESULTS</b>When INS or CeA was stimulated, inducing an obvious increase of blood pressure. To stimulate INS or CeA after microinjecting lidocaine into Hb 5 minutes, the amplitudes of the vasopressor responses were decreased significantly, and the decrease of the bilaterally was larger (decreased value 41.7% in INS, 46.1% in CeA) than that of unilaterally (decreased value 36.9% in INS, 39.6% in CeA).</p><p><b>CONCLUSION</b>Habenula is one of the main relays involved in the vasopressor effects induced by the stimulus of insular cortex, central-, lateral amygdaloid nucleus.</p>