Role of the central interleukin-1 in stress responses / 生理学报
Acta Physiologica Sinica
;
(6): 414-420, 2005.
Article
in English
| WPRIM
| ID: wpr-334154
ABSTRACT
The molecules of interleukin-1 (IL-1) system are widely distributed in central nervous system. As a classical pro-inflammatory factor, central IL-1 has diverse biological functions and plays a pivotal role in a number of important physiological and pathophysiological processes. During the past few years, particular attentions have been directed to the stress mediator actions of central IL-1. This paper reviews some recent findings in the studies of central IL-1 functions in stress responses, including the effects of stress on central IL-1, the roles of IL-1 in the initiation of stress responses, the neural circuitries and intracellular signal transduction pathways involved in the central IL-1 mediated stress responses, as well as the actions of central IL-1 on brain high function and behavior under stressful conditions.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
English
Journal:
Acta Physiologica Sinica
Year:
2005
Type:
Article
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