Study of XW630 in promoting estrogen receptor expression in ovariectomized rats / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 101-104, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-334357
ABSTRACT
We adopted firstly the dextran-coated charcoal(DCC) and SP methods to detect estrogen receptor (ER) expression of bone tissue in ovariectomized(OVX) rats. The results demonstrate that in OVX rats, XW630 can significantly promote ER expression in bone tissue and increase the ER content. XW630 is superior to estrone in effectiveness. The results also reveal that the ER expression in OVX rat bone tissue decreases with the lapse of time, indicating that the expression of ER depends on the existence of estrogen.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Piperazines
/
Tetracycline
/
Tetracyclines
/
Bone and Bones
/
Ovariectomy
/
Receptors, Estrogen
/
Rats, Sprague-Dawley
/
Estrogens, Conjugated (USP)
/
Metabolism
Limits:
Animals
Language:
Chinese
Journal:
Journal of Biomedical Engineering
Year:
2002
Type:
Article
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