Clinical experience of 70 cases of cerebral arteriovenous malformations embolization with Onyx, a novel liquid embolic agent / 中华外科杂志
Chinese Journal of Surgery
;
(12): 223-225, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-334371
ABSTRACT
<p><b>OBJECTIVE</b>To report our clinical experience of using Onyx, a new liquid embolic agent, to treat cerebral arteriovenous malformations (AVMs) as well as its efficacy.</p><p><b>METHODS</b>Seventy cases were placed with 6F sheath in the femoral artery after Seldinger puncture and 6F guiding catheter was introduced into the internal carotid artery or vertebral artery, then a microcatheter was navigated into the nidus of AVMs. Slow injection of Onyx under fluoroscopic control was performed to embolize cerebral AVMs using the "plug and push" technique.</p><p><b>RESULTS</b>Thirteen AVM cases (18.6%) were totally occluded by Onyx and 5 cases of which didn't recurrence at 6-month after operation. Thirty-eight cases (54.3%) were subtotally occluded, while another 19 cases (27.1%) were partially embolized. Severe cerebral hemorrhage occurred in 4 cases, 2 of which had mild to severe hemiplegia after operation, and one died. Mild hemiplegia was also found in 1 case due to functional area embolization, and visual field deficit in 2 cases.</p><p><b>CONCLUSIONS</b>Onyx has unique and distinctive superiority in treating cerebral AVMs. Nonetheless, the correct embolization technique should be learned to achieve good clinical results and avoid complications.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Polyvinyls
/
Therapeutics
/
Intracranial Arteriovenous Malformations
/
Dimethyl Sulfoxide
/
Follow-Up Studies
/
Treatment Outcome
/
Embolization, Therapeutic
/
Methods
Type of study:
Observational study
/
Prognostic study
Limits:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Surgery
Year:
2007
Type:
Article
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