The relationship between microalbuminuria and plasma high sensitivity C reactive protein / 中华心血管病杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the relationship between microalbuminuria (MA) and plasma high sensitivity C reactive protein (hsCRP).</p><p><b>METHOD</b>The plasma hsCRP level and urine albumin level of 746 Chinese people were detected with ELISA and analyzed, respectively.</p><p><b>RESULT</b>The hsCRP level of MA group increased significantly compared with the control group (2.23 +/- 3.35 mg/L vs 1.68 +/- 2.58 mg/L, P < 0.05), the incidence of MA increased significantly when the plasma hsCRP level was beyond 0.77 mg/L (P < 0.05); logistic analysis showed that the occurrence of MA was associated with the plasma hsCRP level (OR = 1.153, P < 0.05).</p><p><b>CONCLUSION</b>Increased plasma hsCRP was probably involved in the occurrence of MA, suggesting that inflammation may deteriorate endothelial dysfunction.</p>