Ooplasmic transfer: problems and prospects / 南方医科大学学报
Journal of Southern Medical University
;
(12): 1079-1082, 2006.
Article
in English
| WPRIM
| ID: wpr-334991
ABSTRACT
Cytoplasmic transfer between human oocytes, which represents a complete cytoplasmic exchange, has been performed recently as a means to improve the outcome of assisted reproduction and becomes a hotspot of researches. Many studies have indicated that mitochondria in the oocytoplasm obviously affect fertilization of the oocytes and early embryo development. However, ooplasmic transfer can lead to mitochondrial DNA heteroplasmy and the prospect of mitochondrial heteroplasmy and its potential problems necessitate further studies. The authors reviews the ooplasmic transfer, the relation between ooplasm and fertilization and embryo development, and the mitochondrial heteroplasmy. The authors also propose a new theory of "reverse cloning technique".
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oocytes
/
Transplantation
/
Fertilization in Vitro
/
Oocyte Donation
/
Cell Biology
/
Cytoplasm
/
Embryonic Development
/
Methods
Limits:
Female
/
Humans
Language:
English
Journal:
Journal of Southern Medical University
Year:
2006
Type:
Article
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