Investigation of viral pathogens contributing to habitual abortion / 南方医科大学学报
Journal of Southern Medical University
;
(12): 1020-1022, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-335003
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the association of Coxsackie B virus (CBV) with habitual abortion.</p><p><b>METHODS</b>CBV IgM antibody, viral RNA and virions were detected in 86 women with habitual abortion and 40 with induced abortion by means of enzyme-linked immunosorbent assay (ELISA), RT-PCR and virus isolation, respectively.</p><p><b>RESULTS</b>The positivity rate of CBV IgM were 87.2% and 35% in the two groups, respectively, and the detection rate of the viral RNA was 53.5% and 17.5% in blood lymphocytes, and 59.3% and 17.5% in the placentas. The virions were found in the placentas in 41.9% and 6.9% of the women, respectively. The positivity rates of CBV IgM, viral DNA and virions showed significant difference between the two groups (P<0. 01).</p><p><b>CONCLUSION</b>CBV might be one of the causes responsible for habitual abortion.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pregnancy Complications, Infectious
/
Virology
/
Blood
/
Immunoglobulin M
/
RNA, Viral
/
Lymphocytes
/
Microscopy, Electron
/
Abortion, Habitual
/
Enterovirus B, Human
/
Coxsackievirus Infections
Limits:
Adult
/
Female
/
Humans
/
Pregnancy
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2006
Type:
Article
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