Healing the mucosa in Crohn's disease: does it matter?
Singapore medical journal
; : 185-189, 2013.
Article
in En
| WPRIM
| ID: wpr-335413
Responsible library:
WPRO
ABSTRACT
Clinical remission has been the therapeutic goal of Crohn's disease treatment for many years. While it has helped to ameliorate the symptoms, this treatment strategy has not brought about significant changes in the need for abdominal surgery in the natural history of Crohn's disease. The advent of biological agents (biologics) has shown that it is possible to induce and maintain mucosal healing in a significant proportion of treated patients. Data is also emerging to show that this has translated to fewer instances of hospitalisation and surgery for these patients. This is a paradigm shift in the therapeutic goal of Crohn's disease treatment.
Full text:
1
Index:
WPRIM
Main subject:
Pathology
/
Therapeutics
/
Ulcer
/
Biological Products
/
Remission Induction
/
Diagnostic Imaging
/
Crohn Disease
/
Treatment Outcome
/
Therapeutic Uses
/
Endoscopy
Type of study:
Diagnostic_studies
Limits:
Humans
Language:
En
Journal:
Singapore medical journal
Year:
2013
Type:
Article