Treatment of recurrent vulvo-vaginal candidiasis with sustained-released butoconazole pessary
Singapore medical journal
;
: e269-71, 2012.
Article
in English
| WPRIM
| ID: wpr-335474
ABSTRACT
Vulvo-vaginal candidiasis (VVC) is a common infection among women. 5% of women with acute infection experience recurrent vulvo-vaginal candidiasis (RVVC). There is currently no optimal or recommended regime for RVVC. Although antifungal agents, such as imidazoles, have been successfully used as a first-line treatment for acute VVC, its effectiveness is limited in RVVC. This could be due to patient factors, drug application (such as leakage) or dosing factors. A sustained-release (SR) bioadhesive vaginal cream (2% butoconazole nitrate) has incorporated VagiSite technology, a topical drug delivery system that allows SR of the drug. We describe its efficacy and the successful use of a butoconazole-SR formulation in the treatment of two cases of RVVC.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pessaries
/
Recurrence
/
Candidiasis, Vulvovaginal
/
Drug Therapy
/
Imidazoles
/
Antifungal Agents
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
Singapore medical journal
Year:
2012
Type:
Article
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