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Profile and Correlates of Health-related Quality of Life in Chinese Patients with Coronary Heart Disease / 中华医学杂志(英文版)
Chinese Medical Journal ; (24): 1853-1861, 2015.
Article in English | WPRIM | ID: wpr-335695
ABSTRACT
<p><b>BACKGROUND</b>Although coronary heart disease (CHD) is one of the major cardiovascular diseases, risk factors associated with the health-related quality of life (HRQoL) of CHD patients remain unclear. The present study was designed to determine the profile and significant factors of the HRQoL in CHD patients.</p><p><b>METHODS</b>A cross-sectional study was conducted in rural communities of Fangshan District, Beijing, China. Socio-demographic, lifestyle, and comorbidity information of CHD patients were collected by a structured questionnaire and medical records. HRQoL was measured using European Quality of Life 5-dimensions (EQ-5D) scale and EQ Visual Analog Scale (EQ-VAS). Multiple linear and logistic regressions were performed to explore the association of potential risk factors with HRQoL scores and each EQ-5D, respectively.</p><p><b>RESULTS</b>Totally, 1928 CHD patients (mean age 61.64 ± 9.24 years; femalemale = 2.41) were enrolled in the study. The mean score of EQ-5D index and EQ-VAS were 0.889 ± 0.172 and 71.56 ± 17.65, respectively. Multiple linear regression revealed that marital status, physical activity, moderate alcohol drinking, and family's population were positive independent correlates of EQ-VAS, whereas diabetes mellitus and stroke were negative independent correlates (all P < 0.05). Age and stroke were negatively while physical activity, moderate alcohol drinking, family's population and household income were positively correlated with EQ-5D index (all P < 0.05) independently. In addition, each of the five HRQoL dimensions had various specific determinants, including obesity, underweight, smoking or education.</p><p><b>CONCLUSIONS</b>Findings of the study highlight certain socio-demographic, lifestyle factors, and comorbid stroke or diabetes mellitus as correlates of HRQoL in Chinese CHD patients. Large-scale cohort studies should be carried out to confirm our results in the future.</p>
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Quality of Life / Socioeconomic Factors / Linear Models / China / Epidemiology / Cross-Sectional Studies / Risk Factors / Coronary Disease Type of study: Etiology study / Observational study / Prevalence study / Prognostic study / Qualitative research / Risk factors Limits: Aged / Aged80 / Female / Humans / Male Country/Region as subject: Asia Language: English Journal: Chinese Medical Journal Year: 2015 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Quality of Life / Socioeconomic Factors / Linear Models / China / Epidemiology / Cross-Sectional Studies / Risk Factors / Coronary Disease Type of study: Etiology study / Observational study / Prevalence study / Prognostic study / Qualitative research / Risk factors Limits: Aged / Aged80 / Female / Humans / Male Country/Region as subject: Asia Language: English Journal: Chinese Medical Journal Year: 2015 Type: Article