A new naphthalene derivative from Aloe vera and its antibacterial activity / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 3761-3763, 2017.
Article
in Zh
| WPRIM
| ID: wpr-335787
Responsible library:
WPRO
ABSTRACT
A new naphthalene derivative has been isolated from Aloe vera by using various chromatographic techniques, including silica gel, sephadex, MCI-gel resin, and RP-HPLC. The new compound was determined as 3-hydroxy-1-(1,7-dihydroxy-3,6-dimethoxynaphthalen-2-yl)propan-1-one (1). In the biological activity assay, compound 1 disglayed prominent antibacterial activity with a MIC90 value of (48±4) mg•L⁻¹ for methicillin resistant Staphylococcus aureus (MRSA) strain which was stronger than that of the positive control levofloxacin with a MIC90 value (58±5) mg•L⁻¹.
Full text:
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Index:
WPRIM
Language:
Zh
Journal:
China Journal of Chinese Materia Medica
Year:
2017
Type:
Article