Influence factors for hepatotoxicity of traditional Chinese medicine preparations / 中国中药杂志

ABSTRACT

Traditional Chinese medicine(TCM) preparation is one of the most important aspects in the development and quality control of traditional Chinese medicine, and its security problem becomes more and more serious. It is worthy to note that the liver, as the main drug metabolic organ, bears the brunt of the damage caused by TCM preparations. In this paper, the author attempts to explore the relationship between TCM preparations and hepatotoxicity based on the processing chains from crude drugs to the end product. Besides, the author hopes to clarify the underlying mechanism of hepatotoxicity of TCM preparations and provide basis and guidance for the quality control and rational clinical use of the preparations as well as the development of modern TCM preparations with high quality and low toxicity.