Cell adhesion molecules in human embryo implantation / 生理学报
Acta Physiologica Sinica
;
(6): 247-258, 2012.
Article
in English
| WPRIM
| ID: wpr-335916
ABSTRACT
The process of human embryo implantation is mediated not only by evolutionarily conserved mechanisms, but also by a mechanism unique to humans. Evidence suggests that the cell adhesion molecules, L-selectin and trophinin, play a unique role in human embryo implantation. Here, we describe the dual roles of mucin carbohydrate ligand for L-selectin and trophinin protein and of the trophinin-associated proteins bystin and tastin. We then describe trophinin-mediated signal transduction in trophectoderm cells and endometrial epithelial cells. This review also covers cadherin and integrin in human embryo implantation.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Embryo Implantation
/
Physiology
/
Signal Transduction
/
Cadherins
/
Cell Adhesion Molecules
/
Integrins
/
L-Selectin
/
Epithelial Cells
/
Metabolism
Limits:
Humans
Language:
English
Journal:
Acta Physiologica Sinica
Year:
2012
Type:
Article
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