Cellular function of microRNA-15 family / 生理学报
Acta Physiologica Sinica
; (6): 101-106, 2012.
Article
in Zh
| WPRIM
| ID: wpr-335935
Responsible library:
WPRO
ABSTRACT
microRNAs (miRNAs) are non-coding endogenous short RNAs which are involved in regulating gene expression at the post-transcriptional level. miR-15 family is increasingly found to play great roles in important cell processes, such as apoptosis, cell differentiation and stress response. Growing evidence indicates that miR-15 family members are implicated in tumor, cardiovascular disease and neurodegenerative disease. miRNAs have emerged as a new promising subset of therapeutic targets. The present paper reviewed the important function of miR-15 family and new approaches for miRNA-based therapy.
Full text:
1
Index:
WPRIM
Main subject:
Pathology
/
Physiology
/
Molecular Sequence Data
/
Base Sequence
/
Cell Cycle
/
Cell Differentiation
/
Gene Expression Regulation
/
Apoptosis
/
MicroRNAs
/
Genetics
Limits:
Animals
/
Humans
Language:
Zh
Journal:
Acta Physiologica Sinica
Year:
2012
Type:
Article