Imaging features of primary pulmonary lymphoepithelioma-like carcinoma: report of 10 cases and literature review / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To study the imaging features of primary pulmonary lymphoepitheliom-like carcinoma (LELC).</p><p><b>METHODS</b>Ten cases of primary pulmonary LELC were confirmed by surgery and pathology. The findings in clinical pathology, X-ray and CT were retrospectively analyzed and the related references were reviewed.</p><p><b>RESULTS</b>The clinical manifestations included coughing (5 cases), hemoptysis (2 cases), chest distress (4 cases), thoracodynia (3 cases), and fever (2 cases), with 3 cases being asymptomatic. Radiographically, primary pulmonary LELC appeared mainly as peripheral nodules or masses. The maximum diameter of the lesion was 2.3 to 12.4 cm. The lesions were slightly lobulated in 7 cases and spiky on the edge in 3 cases. Pleura retraction was shown in 3 cases. CT contrast scanning revealed light or significant enhancement in 5 cases.</p><p><b>CONCLUSION</b>Primary pulmonary LELC has some characteristic imaging features, but X-ray and CT only are not sufficient for a definite diagnosis, which still relies on bronchoscopic biopsy and percutaneous pulmonary puncture biopsy.</p>