Volumetric MRI analysis of the amygdala and hippocampus in subjects with major depression / 华中科技大学学报(医学)(英德文版)
Journal of Huazhong University of Science and Technology (Medical Sciences)
;
(6): 500-506, 2004.
Article
in English
| WPRIM
| ID: wpr-336998
ABSTRACT
In order to explore the MRI volume of the amygdala and hippocampus in patients with major depression, quantitative MRI of the amygdala and hippocampus were studied in 22 patients with major depression and compared with 13 age-matched controls. The results showed that both groups exhibited similar significant hippocampal asymmetry (left smaller than right). The volume of the bilateral hippocampus was significantly smaller in the major depression group than that in control group. The patients had significant asymmetry of the amygdalar volumes (right smaller than left). No correlation was found between hippocampal volume abnormalities and ill duration. It was concluded that the hippocampus and amygdala within limbic-cortical networks may play a crucial role in the pathogenesis of major depression.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Magnetic Resonance Imaging
/
Anthropometry
/
Depressive Disorder, Major
/
Hippocampus
/
Amygdala
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
Journal of Huazhong University of Science and Technology (Medical Sciences)
Year:
2004
Type:
Article
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