Laryngeal histoplasmosis: an occupational hazard
Singapore medical journal
;
: e208-10, 2013.
Article
in English
| WPRIM
| ID: wpr-337856
ABSTRACT
Isolated laryngeal histoplasmosis is a very rare entity. It has variable clinical presentations that might mimic both benign and malignant lesions, and is usually associated with pulmonary and other disseminated forms of histoplasmosis. Herein, we report a case of primary laryngeal histoplasmosis without the involvement of other systems in a 70-year-old Chinese man, who previously worked as a miner. He presented with a history of hoarseness for two months, with no other associated symptoms. Direct laryngoscopy revealed irregularity of the posterior one-third of both vocal folds. Histopathological examination revealed the presence of Histoplasma capsulatumon periodic acidSchiff and Grocott's methenamine silver staining. The lesion resolved after one month of oral itraconazole treatment. However, the patient had to complete six months of antifungal treatment to prevent recurrence.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Amphotericin B
/
Laryngitis
/
Occupational Exposure
/
Therapeutic Uses
/
Diagnosis
/
Drug Therapy
/
Histoplasma
/
Histoplasmosis
/
Laryngoscopy
Type of study:
Diagnostic study
Limits:
Aged
/
Humans
/
Male
Language:
English
Journal:
Singapore medical journal
Year:
2013
Type:
Article
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