Genetic polymorphism of FMO3 and its role in drug metabolism and toxicity / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 2701-2705, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-337905
ABSTRACT
The flavin-containing monooxygenase 3 (FMO3) is an important hepatic microsomal enzyme. Numerous mutations of FMO3 gene have been reported, and polymorphic varients of the gene have been identified. Several studies indicated that variability in the expression of FMO3 involved in some nitrogen, or sulfur-containing durg metabolism. This review summarizes the genetic polymorphism of FMO3 and its role in drug metabolism and toxicity.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oxygenases
/
Polymorphism, Genetic
/
Drug-Related Side Effects and Adverse Reactions
/
Genetics
Limits:
Humans
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2015
Type:
Article
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