Plasma endothelin-1 in patients with prostate cancer and its clinical significance / 中华男科学杂志
National Journal of Andrology
;
(12): 315-322, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-338304
ABSTRACT
<p><b>OBJECTIVE</b>To investigate plasma endothelin-1 (ET-1) level in patients with prostate cancers and its clinical significance.</p><p><b>METHODS</b>Plasma ET-1 level was measured by radioimmunoassay in 31 patients of prostate cancer (23 with non-HRPC, 8 with HRPC) and 26 patients of BPH.</p><p><b>RESULTS</b>Compared with each other of the ET-1 level, there were no significant difference among the BPH group,non-HRPC group and HRPC group. No significant difference was found either between bone metastasis (BM) and non- BM, between high and middling differentiation prostate cancer group, as well as in different PSA level groups (P >0.05). But the ET-1 level in low differentiation prostate cancer was notably lower than those of the high and middle respectively (P < 0.05).</p><p><b>CONCLUSION</b>To detect plasma endothelin-1 (ET-1) level is not a useful method to evaluate the development and the prognosis of prostate cancer.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Prostatic Hyperplasia
/
Prostatic Neoplasms
/
Blood
/
Radioimmunoassay
/
Endothelin-1
Type of study:
Prognostic study
Limits:
Aged
/
Aged80
/
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2006
Type:
Article
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