Study on HPLC characteristic fingerprint of active components of dachuanxiong fang in plasma and cerebrospinal fluid / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 2017-2021, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-338713
ABSTRACT
<p><b>OBJECTIVE</b>To establish an accurate and simple qualitative analytical method in vivo in the study on HPLC characteristic fingerprint of active components of dachuanxiong fang in plasma and cerebrospinal fluid, in order to lay a foundation for studies on components found in plasma and cerebrospinal fluid and provide basis for compatible regularity of initiators.</p><p><b>METHOD</b>HPLC characteristic fingerprint of active components of dachuanxiong fang in plasma and cerebrospinal fluid was established.</p><p><b>RESULT</b>The similarity of fingerprints of all of six batches of samples was above 0.85, RSD of their relative retention times in common peaks was less than 2. 0%.</p><p><b>CONCLUSION</b>The fingerprints of active components of dachuanxiong fang in plasma and cerebrospinal fluid were stable and accurate that they can be used in qualitative analysis on in vivo components.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Quality Control
/
Blood
/
Drugs, Chinese Herbal
/
Plant Extracts
/
Cerebrospinal Fluid
/
Chromatography, High Pressure Liquid
/
Rats, Sprague-Dawley
/
Medicine, Chinese Traditional
/
Metabolism
/
Methods
Type of study:
Diagnostic study
/
Qualitative research
Limits:
Animals
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2012
Type:
Article
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