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Drug-eluting stent implantation for unprotected left main coronary artery disease: immediate and long-term outcomes / 南方医科大学学报
Journal of Southern Medical University ; (12): 2257-2259, 2008.
Article in Chinese | WPRIM | ID: wpr-339086
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the safety and efficacy of drug-eluting stent (DES) implantation in selective patients with left main coronary artery disease.</p><p><b>METHOD</b>From October 2002 to November 2007, 44 consecutive patients underwent percutaneous coronary interventions (PCI) on left main coronary artery lesions, including 5 patients with concurrent left ventricular dysfunction (ejection fraction<40%), 2 with chronic respiratory dysfunction and 5 with chronic renal failure. The findings in coronary angiography, procedural success rate, severe complications and the follow-up results of the patients were analyzed.</p><p><b>RESULTS</b>The immediate procedural success rate was 100% in these patients without any severe complications. No non-fatal acute myocardial infarction or emergency coronary artery bypass grafting (CABG) was performed and death occurred in none of the cases during hospitalization. In the follow-up period for 14.2-/+9.3 (6-65) months after PCI, no subacute or late thromboses were found. One patient died from heart failure 4 months after PCI, and 6 patients (13.6%) experienced recurrent angina. Thirty-seven patients (84.1%) were free of any major cardiovascular events (MACE) after the procedure. A repeat coronary angiography was performed in 35 patients (79.5%) within 6 months after PCI, and 3 (8.6%) of them were confirmed to have restenosis, including 1 patient with distal bifurcation restenosis who were subsequently treated with CABG and two patients with side-branch ostium restenosis managed with cutting balloon dilation.</p><p><b>CONCLUSIONS</b>Implantation of drug-eluting stents is safe and effective for management of left main coronary artery disease with good immediate and long-term outcomes.</p>
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Therapeutics / Coronary Artery Disease / Angioplasty, Balloon, Coronary / Follow-Up Studies / Treatment Outcome / Coronary Angiography / Coronary Restenosis / Drug-Eluting Stents Type of study: Observational study / Prognostic study Limits: Adult / Aged / Female / Humans / Male Language: Chinese Journal: Journal of Southern Medical University Year: 2008 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Therapeutics / Coronary Artery Disease / Angioplasty, Balloon, Coronary / Follow-Up Studies / Treatment Outcome / Coronary Angiography / Coronary Restenosis / Drug-Eluting Stents Type of study: Observational study / Prognostic study Limits: Adult / Aged / Female / Humans / Male Language: Chinese Journal: Journal of Southern Medical University Year: 2008 Type: Article