Preliminary result on pediculoplasty for treatment of vertebral pedicular osteolytic metastasis of lung cancer / 中国肺癌杂志

ABSTRACT

<p><b>BACKGROUND</b>Vertebral pedicular metastasis in lung cancer patients are common. This is a preliminary study on methods and clinical application of percutaneous pediculoplasty in the treatment of vertebral pedicular osteolytic metastasis of lung cancer.</p><p><b>METHODS</b>Percutaneous pediculoplasty was performed in 5 lung cancer patients with osteolytic metastasis in 7 vertebral pedicles, 2 cases occurred in thoracic vertebral pedicles and 3 cases occurred in lumbar vertebral pedicles, 2 cases had two loci involved. Under Multislice helical CT guidance, 2.5-5mL of polymethylmethacrylate mixture (ratio of polymer, moner, ultrafluid iodinated oil was 20g10mL3mL) had been injected into pathologic pedicles step by step after successful puncture using 13G needle. All cases had been followed-up in 2-5 months.</p><p><b>RESULTS</b>All cases had been successfully punctured. Pain relieved in all 4 cases to some extent after percutaneous pediculoplasty. Two cases had bone-cement leakage, 1 case with leakage into intervertebral foramen which led to nerve radicular pain, the pain disappeared 3 days later after intravenous mannitol and lower dose dexamethasone drips, and another 1 case with minor leakage into vertebral canal but without clinical symptoms. No spondyloptosis occurred in all cases after follow-up.</p><p><b>CONCLUSIONS</b>CT-guided percutaneous pediculoplasty is a minimal injured, effective and safe method for osteolytic vertebral pedicular metastasis of lung cancer.</p>