Long term survival results in advanced prostate cancer treated with combined androgen blockade / 中华男科学杂志
National Journal of Andrology
;
(12): 770-774, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-339429
ABSTRACT
<p><b>OBJECTIVE</b>To understand long-term survival rate after combined androgen blockade (CAB) in patients with advanced prostate cancer.</p><p><b>METHODS</b>A selected population of 59 patients with advanced prostate cancer were treated with CAB. 28.81% (17/59) of patients had clinical locally advanced disease (stage T3-4N0M0), and 45.76% (27/59) of patients had metastatic disease (stage TxNxM+). Overall, patients were followed for a median of 62 (range 6-136) months.</p><p><b>RESULTS</b>Of the 59 patients with advanced prostate cancer, 3-year, 5-year and 7-year overall survival rates were 79.36%, 61.46% and 49.15%, respectively. The 5-year survival rate were 80.77% and 32.65% for clinical locally advanced disease and metastatic disease. Specifically, men with poorly differentiated prostate cancer had a 5-year survival of only 30% when compared with men with well-differentiated prostate disease who had a 5-year survival of 86.21%.</p><p><b>CONCLUSION</b>Based on these findings, men with poorly differentiated cancer, stage T3c-4NxMx or TxNxM+ and PSA level above 30 microg/L had a high probability of dying from their advanced prostate cancer.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prostatic Neoplasms
/
General Surgery
/
Survival Rate
/
Follow-Up Studies
/
Mortality
/
Combined Modality Therapy
/
Therapeutic Uses
/
Drug Therapy
/
Flutamide
/
Androgen Antagonists
Type of study:
Observational study
/
Prognostic study
Limits:
Aged
/
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2005
Type:
Article
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