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Gene expression profiling in porcine fetal thymus / 基因组蛋白质组与生物信息学报·英文版
Genomics, Proteomics & Bioinformatics ; (4): 171-172, 2003.
Article in English | WPRIM | ID: wpr-339510
ABSTRACT
To obtain an initial overview of gene diversity and expression pattern in porcine thymus, 11,712 ESTs (Expressed Sequence Tags) from 100-day-old porcine thymus (FTY) were sequenced and 7,071 cleaned ESTs were used for gene expression analysis. Clustered by the PHRAP program, 959 contigs and 3,074 singlets were obtained. Blast search showed that 806 contigs and 1,669 singlets (totally 5,442 ESTs) had homologues in GenBank and 1,629 ESTs were novel. According to the Gene Ontology classification, 36.99% ESTs were cataloged into the gene expression group, indicating that although the functional gene (18.78% in defense group) of thymus is expressed in a certain degree, the 100-day-old porcine thymus still exists in a developmental stage. Comparative analysis showed that the gene expression pattern of the 100-day-old porcine thymus is similar to that of the human infant thymus.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Thymus Gland / Genetic Variation / Sequence Analysis, DNA / Computational Biology / Expressed Sequence Tags / Gene Expression Profiling / Sus scrofa / Fetus / Genetics / Metabolism Limits: Animals Language: English Journal: Genomics, Proteomics & Bioinformatics Year: 2003 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Thymus Gland / Genetic Variation / Sequence Analysis, DNA / Computational Biology / Expressed Sequence Tags / Gene Expression Profiling / Sus scrofa / Fetus / Genetics / Metabolism Limits: Animals Language: English Journal: Genomics, Proteomics & Bioinformatics Year: 2003 Type: Article