Chromosome analysis in 92 children with congenital mental retardation / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 651-653, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-339570
ABSTRACT
<p><b>OBJECTIVE</b>To explore the chromosome karyotypes in children with mental retardation.</p><p><b>METHODS</b>The peripheral blood lymphocytes from 92 children with congenital mental retardation were cultured and analysed by the G-band technique.</p><p><b>RESULTS</b>Of the 92 cases, 43 cases (47%) showed chromosome abnormalities. Autosomal abnormalities were found in 35 cases (38%) and sex chromosome abnormalities were found in 8 cases (9%). A novel abnormal karyotype 45, XX, psu dic (11;9) (p15;p24) was found in a child.</p><p><b>CONCLUSIONS</b>Chromosome abnormalities may be important cytogenetic factors for congenital mental retardation. Cytogenetic chromosome karyotypic analysis appears to be an important method for genetic screening of congenital mental retardation.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Sex Chromosome Aberrations
/
Genetic Testing
/
Chromosome Aberrations
/
Genetics
/
Karyotyping
/
Intellectual Disability
Type of study:
Prognostic study
Limits:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
Chinese
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2011
Type:
Article
Similar
MEDLINE
...
LILACS
LIS