The analysis of hantavirus S gene in Apodemus agrarius in Changbai area / 病毒学报
Chinese Journal of Virology
;
(6): 382-385, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-339941
ABSTRACT
To gain more insights into epidemiologic characteristics and genotype of hantavirus in Apodemus agrarius in Changbai Area. Complete hantavirus S segment sequences were amplified by RT-PCR and sequenced. The phylogenetic trees were constructed for analysis of genetic characters of hantavirus. A total of 58 Apodemus agrarius were trapped in the epidemic areas, and complete hantavirus S segment sequences were obtained from 4 lung samples of these rodents (6. 90%0). Phylogenetic analysis of the four S segment sequences indicated that all viruses isolated from Apodemu sagrarius were closely related to genotype 6 of Hantaan virus (95. 8%-96. 3%, nucleotide identity; 98. 6%-99. 5%, amino acid identity), all of them had a specific S387 different from other genotypes of Hantaan virus.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phylogeny
/
Rodent Diseases
/
Viral Proteins
/
Virology
/
Disease Reservoirs
/
RNA, Viral
/
Base Sequence
/
Chemistry
/
China
/
Epidemiology
Limits:
Animals
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Virology
Year:
2013
Type:
Article
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