Research on the gene structure of duck hepatitis B virus and its encoding proteins / 病毒学报
Chinese Journal of Virology
;
(6): 681-688, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-339985
ABSTRACT
Duck hepatitis B virus (DHBV) belongs to the Avihepadnavirus genus of the Hepadnaviridae, and it not only has the same replication pattern, but also has the similar genomic and antigenic structures to Hepatitis B virus (HBV). The genome of DHBV is a partially double-stranded closed circular DNA. The genome consists of three distinct open reading frames (ORFs) ORF-PreS/S, ORF-PreC/C and ORF-P, which all locate on the negative DNA strand and encode four separate proteins. The ORF-PreS/S encodes envelope proteins L and S, and the ORF-PreC/C and ORF-P encode capsid proteins C and polymerase proteins P, respectively. The characteristics of genome structure,viral proteins features and functions were described in this review in order to provide useful information for the further study of DHBV and the duck model infected by DHBV.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Viral Proteins
/
Virology
/
Hepatitis B Virus, Duck
/
Chemistry
/
Open Reading Frames
/
Protein Structure, Tertiary
/
Hepadnaviridae Infections
/
Ducks
/
Genetics
/
Hepatitis, Viral, Animal
Type of study:
Prognostic study
Limits:
Animals
Language:
Chinese
Journal:
Chinese Journal of Virology
Year:
2012
Type:
Article
Similar
MEDLINE
...
LILACS
LIS