Difference in lymphocyte heat shock protein 71 (HSP71) expression in soldiers of armed police forces from different climatic zones / 中华劳动卫生职业病杂志
Chinese Journal of Industrial Hygiene and Occupational Diseases
;
(12): 282-284, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-340082
ABSTRACT
<p><b>OBJECTIVE</b>To analyze the difference between basal and heat-inducible levels of lymphocyte heat shock protein 71 (HSP71) expression in soldiers from Beijing, Zhengzhou and Guangzhou.</p><p><b>METHODS</b>Flow cytometry and Comet assay were used to detect the level of HSP71 and DNA damage respectively.</p><p><b>RESULTS</b>Comet assay showed that there was no significant DNA damage before and after heat stress at 41 degrees C for 1 h, and also no difference found among the 3 climatic zones(P > 0.05). HSP71 of all soldiers in the 3 zones elevated after stress (P < 0.05). The basal and heat-inducible levels of HSP71 in Beijing soldiers(845.87 +/- 135.60 and 1254. 47 +/- 239.05 mean fluorescence intensity respectively) were higher than those in Guangzhou soldiers(702.73 +/- 184.70 and 861.72 +/- 225.12 mean fluorescence intensity respectively) (P < 0.05).</p><p><b>CONCLUSION</b>The differences of lymphocyte HSP71 expression before and after heat stress among the soldiers from Beijing, Zhengzhou and Guangzhou suggest that basal and heat-inducible levels of lymphocyte HSP71 expression may be considered as a valuable index to evaluate heat tolerance of soldiers in different climatic zones.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
DNA Damage
/
Lymphocytes
/
Police
/
Climate
/
Heat Stress Disorders
/
Comet Assay
/
Flow Cytometry
/
Heat-Shock Proteins
/
Metabolism
/
Military Personnel
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Industrial Hygiene and Occupational Diseases
Year:
2002
Type:
Article
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